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Gentle daily care for periodontitis and sensitive gums

Bleeding gums when brushing. Sensitive gums that don’t improve. Or a dental appointment where, for the first time, the word “periodontitis” comes up. Panaceo Care Zeolite Toothpaste was developed for everyone who expects more from their daily oral care – without compromising on ingredients.

Person with healthy gums smiles calmly, next to them Panaceo Care Zeolite Toothpaste
What the study shows

Clinically investigated – at a glance

2 out of 3

participants reported noticeably improved oral comfort after 10 weeks

10 weeks

Use alongside professional periodontal therapy

36

patients with chronic periodontitis investigated in the study

without fluoride, titanium dioxide & chlorhexidine

A different approach

Why Panaceo Care Zeolite Toothpaste?

Most toothpastes for periodontitis rely on antibacterial actives such as chlorhexidine or stannous fluoride. They fight bacteria broadly and non‑specifically – in the case of chlorhexidine with known side effects when used long term. PMA®-Zeolith takes a different path.

Conventional antiseptics

  • Kill bacteria broadly & non‑specifically
  • Chlorhexidine: possible tooth discolouration
  • Known to cause taste disturbances
  • Disrupt the oral microbiome with long‑term use
  • Not suitable for long‑term use
PMA®-Zeolith

Natural mineral

  • Physical approach – does not indiscriminately kill bacteria
  • Supports the binding of bacterial deposits
  • In the study: positive shift in microbiome balance
  • Developed for daily, long‑term use
  • Without the known side effects of conventional antiseptics
Oral microbiome

The milieu decides – how PMA®-Zeolith supports balance in the mouth

Hardly anyone thinks about it, but the mouth – much like the gut – has its own microbiome. Billions of microorganisms form a finely balanced protective system that keeps the mucous membranes stable and supports the immune system.

If this balance starts to wobble, inflammation‑promoting bacteria gain the upper hand – the very germs that persist above all in deep periodontal pockets.

This is precisely where PMA®-Zeolith comes in: the natural mineral binds acids, toxins, bacterial metabolites and heavy metals. In doing so, it deprives harmful germs of their means of survival – and creates space for microorganisms that favour regeneration.

Abstract illustration of a balanced oral microbiome with microorganisms in equilibrium
What the study’s microbiome analysis shows

Desulfobulbus oralis – declining

Inflammation‑associated bacteria declined markedly over the course of the study.

Lachnospiraceae – increasing

Health‑associated genera increased over the same period.

PMA®-Zeolith therefore does not act against individual bacteria, but changes the entire milieu – until health becomes possible again.

“The microbe is nothing; the milieu is everything.”

Antoine Béchamp, French scientist

Béchamp formulated this idea over a hundred years ago – and it gets to the heart of what modern research knows about periodontitis and many other inflammatory diseases: it is not the bacteria themselves that are the real problem, but the conditions under which they spread. Only when the milieu tips – due to stress, heavy metals, diet, biofilms or an unstable microbiome – does inflammation take its destructive course. PMA®-Zeolith targets exactly that: the milieu.

Clinically investigated

No laboratory promise – investigated in real patients

The crucial difference compared to many oral care products is not only the active ingredient itself, but the fact that this active was investigated in real patients. PMA®-Zeolith was examined in a controlled clinical study, published in 2025 and indexed on PubMed (PMID: 40863290).

Study design
  • 36 patients with chronic periodontitis
  • Control group with 6 patients
  • 10 weeks of use, alongside professional periodontal therapy
  • Follow‑up after 12 weeks
Observed results

Over the course of the study, significant improvements were observed in all key clinical parameters:

  • Plaque index significantly reduced
  • Bleeding on probing (BOP) significantly reduced
  • Probing depths significantly reduced
  • Positive change in the bacterial composition of the oral microbiome
2 out of 3

study participants reported a noticeable improvement in oral comfort after 10 weeks.

Important note: The study investigated PMA®-Zeolith as part of an adjunctive treatment concept in combination with professional periodontal therapy. The toothpaste does not replace a dental diagnosis or treatment.
Thoughtfully formulated

Naturally caring – consciously pared back

The formulation of Panaceo Care Zeolite Toothpaste has been deliberately pared back to the essentials – for anyone who wants no compromises on ingredients in their daily oral care.

Without titanium dioxide
Fluoride‑free
Without microplastics
Without synthetic sweeteners
Vegan
Certified natural cosmetics
Made in Austria
Made for you

Who is Panaceo Care Zeolite Toothpaste suitable for?

The toothpaste is particularly suitable for people seeking a clinically investigated, natural oral care product for daily use.

Sensitive gums

For anyone with sensitive gums or occasional bleeding gums.

Adjunct to periodontal treatment

During or after professional periodontal treatment – as daily adjunctive care.

Choosing to avoid

For anyone who wishes to avoid chlorhexidine, titanium dioxide or fluoride.

Natural cosmetics with science

For anyone who prefers natural cosmetics but values scientifically investigated ingredients.

For daily use

For anyone seeking a toothpaste for long‑term use – without the known side effects of conventional antiseptics.

Transparency

Ingredients and their properties

PMA®-Zeolith

Patented natural mineral; supports the physical removal of bacterial deposits; investigated in a clinical study for effects on the composition of the oral microbiome.

Aloe vera

Soothes sensitive gums; mildly moisturising.

Organic chamomile extract*

A traditionally recognised plant extract for gum irritation; from controlled organic cultivation.

Organic peppermint oil*

Long‑lasting fresh feeling in the mouth; mildly antimicrobial; from controlled organic cultivation.

Sodium bicarbonate

Supports the mouth’s natural pH regulation.

Vitamin E

Antioxidant ingredient; supports the natural regeneration of the oral mucosa.

*from controlled organic cultivation

Application

Daily care made simple

Apply a pea‑sized amount

In the morning and evening, place a pea‑sized amount on the toothbrush.

Brush for at least two minutes

Brush your teeth thoroughly for at least two minutes.

Use regularly over 10 weeks

For optimum results, regular use for at least 10 weeks is recommended – matching the duration of the clinical study.

Tip: 1 tube lasts about 4–6 weeks. For the full duration, a 10‑week supply is recommended.
Toothbrush with a pea‑sized amount of Panaceo Care Zeolite Toothpaste next to the opened tube
Twice daily, at least two minutes – your daily oral care ritual.
Frequently asked questions

Answers at a glance

Yes – PMA®-Zeolith was specifically investigated in a controlled clinical study in patients with chronic periodontitis and showed significant improvements in clinical parameters. Important: as an adjunct to professional periodontal therapy, not a substitute for dental treatment.
Conventional actives such as chlorhexidine or stannous fluoride are antibacterial – they inhibit or kill bacteria in the mouth without distinguishing between beneficial and harmful microbes. Chlorhexidine is also not suitable for long‑term use, as it can cause tooth discolouration and taste disturbances. PMA®-Zeolith takes a physical approach and targets the binding of bacterial deposits – without burdening the oral microbiome. In the clinical study, a positive change in the microbial composition was observed.
No. Panaceo Care Zeolite Toothpaste is fluoride‑free – for anyone who consciously wishes to avoid fluoride in their daily oral care.
No. The formulation deliberately contains no titanium dioxide.
Yes, Panaceo Care Zeolite Toothpaste is vegan.
In the clinical study, results were measured after 10 weeks of regular use. Individual experiences may vary. For optimal daily oral care, we recommend continuous use for at least this period.

Mindful oral care, every day.

Panaceo Care Zeolite Toothpaste with clinically investigated PMA®-Zeolith – fluoride‑free, titanium dioxide‑free, vegan. Made in Austria.