Skip to main content Skip to search Skip to main navigation
Health & Immune System

Strengthening the Gut Means Strengthening the Liver

The gut has a major influence on the liver. Learn how the gut-liver axis works, how to recognise a burdened liver and how MED DARM REPAIR with PMA-Zeolite can support the gut and liver.

Published on Approx. 7-minute read By Mag. Sandra Eisenwagen, BSc.
Illustration of the connection between gut and liver – the gut-liver axis
The gut and liver are closely connected via the portal vein and the bile ducts.

The gut has a major influence on our liver. The liver performs numerous metabolic tasks in the body. When it is overburdened, it suffers silently. The good news: it can regenerate quite quickly when you adjust your lifestyle and take further measures. The focus of science here is the gut-liver axis.

What Are the Tasks of the Liver?

The liver stands not only for detoxification but also performs numerous metabolic tasks – around 500 in total. Everything we take in through food and drink, whether food, medication, alcohol or harmful and environmental substances, has to be processed by the liver. Nutrients and pollutants pass from food into the gut and from there via the portal vein into the liver.

What the body needs right now is passed on; substances not immediately required – above all fats, sugars and pollutants – are stored in the liver. Sugar is stored as glycogen and released into the blood as glucose when needed. Alcohol is converted into fat – which is why blood lipid levels are often elevated with excessive alcohol consumption.

The liver also produces vital proteins for blood clotting as well as bile acid. Bile acid ensures that fats and fat-soluble vitamins are released from food. Without bile, the gut could not absorb valuable nutrients. This shows how important a healthy liver is for many processes in the body.

How Do You Notice That the Liver Is Impaired?

When the liver is damaged or burdened, the liver values in the blood are elevated. The most common causes include a high-fat diet, excessive alcohol consumption, regular medication use and pollutants absorbed through food. Viruses (such as hepatitis viruses), bacteria or gallstone diseases can also damage the liver. Most often, however, an unhealthy diet, alcohol or the regular use of medication are responsible.

The Connection Between Gut and Liver

The gut-brain axis is now widely discussed. Numerous scientific publications also confirm the gut-liver axis. The gut – the centre of our health – influences not only the psyche, skin and immune system but also the liver. The liver in particular is directly connected to the gut and its bacteria via the portal vein and the bile ducts.

Many factors such as poor nutrition, stress, medication, illness, environmental factors and inflammation in the gut can impair the function of the intestinal barrier. In this context, science speaks of leaky gut – a permeable intestine.

Zonulin & alpha-1-antitrypsin

The permeability of the intestinal lining is largely regulated by the switch protein zonulin – like a master key, it controls the "intestinal gates". When zonulin is elevated, too many unwanted substances enter the blood and burden the gut, immune system and downstream organs such as the liver. The value alpha-1-antitrypsin also indicates the permeability and possible inflammation of the gut. If both values are elevated, this is considered a sign of leaky gut.

Health, lifestyle and diet therefore have a strong influence on gut and liver health.

How Can MED DARM REPAIR Support Elevated Liver Values?

Science confirms not only the gut-liver axis but also that targeted support of the gut can be an important basis for relieving the liver, since the gut and liver work together as an overall system. Therefore – alongside the medical assessment of the cause – strengthening the gut-liver axis and relieving the liver are also a focus.

Generally, after a medical assessment of the cause, the following measures are recommended:

  • Adjusting your lifestyle.
  • A higher proportion of vegetables and fruit.
  • Bitter substances that stimulate digestion – for example, a glass of warm water with lemon in the morning. The vitamin C it contains additionally supports the liver enzymes.

According to the manufacturer, MED DARM REPAIR can support the intestinal barrier and thus the gut-liver axis by:

  • binding ammonium and pollutants in the gut
  • favourably influencing the gut environment and microbiome
  • contributing to the regeneration of the intestinal lining
  • counteracting intestinal inflammation
  • contributing to the relief of irritable bowel symptoms
  • supporting the liver by relieving the gut

Manufacturer's Study Data on Elevated Liver Values

According to the study data cited by the manufacturer, MED DARM REPAIR contributes to the regeneration of the damaged intestinal wall and counteracts intestinal inflammation. In a study on liver support cited by the manufacturer, reductions in liver enzymes were observed:

GGT −17%

Gamma-glutamyltransferase

GOT −25%

Glutamate oxaloacetate transaminase

GPT −31%

Glutamate pyruvate transaminase

Further studies cited by the manufacturer suggest that MED DARM REPAIR can lower zonulin and alpha-1-antitrypsin levels. Individual results may vary; elevated liver values should always be assessed by a doctor.

More information on the study (technical information as PDF)

Please note

MED DARM REPAIR is a medical device to support gut health – not a cure for liver disease. With elevated liver values, the medical assessment of the cause is crucial. Discuss its use with your doctor.

PANACEO MED DARM REPAIR Powder 200 g with 100% PMA-Zeolite
Matching product

PANACEO MED DARM REPAIR Powder 200 g

Certified medical device with 100% PMA-Zeolite to support the intestinal barrier and the gut-liver axis – as a complement to a medically supervised treatment.

Discover product
Portrait of Mag. Sandra Eisenwagen, BSc.

Mag. Sandra Eisenwagen, BSc.

Head of Research and Development at Panaceo International GmbH in Austria since 2015. Previously an adviser on nutrition and consumer protection at the FAO and the European Commission. Master's degree in Nutritional Sciences (University of Vienna) and studies in Environmental Biology at the Università degli Studi Roma Tre. Focus areas: nutritional science, food safety and microbiology.

Share article

Note: This article is for general information only and does not replace medical advice, diagnosis or treatment. Elevated liver values and liver diseases should be assessed and treated by a doctor. MED DARM REPAIR is a medical device to support gut health and not a cure for liver disease. The study data mentioned are from manufacturer information; individual results may vary.

Frequently asked questions

Questions About Gut, Liver & MED DARM REPAIR

The gut-liver axis describes the close connection between the gut and liver via the portal vein and the bile ducts. When the intestinal barrier is disturbed (leaky gut), more pollutants can burden the liver.

Zonulin regulates the permeability of the intestinal lining. An elevated value – together with an elevated alpha-1-antitrypsin value – is considered an indication of a permeable gut (leaky gut). The assessment belongs in medical hands.

According to the manufacturer and the study data it cites, MED DARM REPAIR can relieve the liver by strengthening the intestinal barrier; reductions in liver enzymes were observed. However, MED DARM REPAIR is not a cure and does not replace the medical assessment and treatment of elevated liver values.

A healthy lifestyle, more vegetables and fruit, sufficient exercise and moderate alcohol use support the liver. With elevated liver values, the cause should always first be assessed by a doctor.

Zeo (digital assistant) AI

You are chatting with an AI assistant. Replies may contain errors and are non-binding.

Hi, I'm Zeo, your digital assistant at PANACEO! How can I help you?