1997
First encounter with the natural mineral zeolite clinoptilolite and the entrepreneur and inventor Jakob Hraschan.
1998
Initiation and financing of initial studies (including toxicity test according to OECD).
2000
Erforschung, Konzeption und Produktion der PMA-Aktivatoren zur Veredelung und Optimierung des Rohmaterials.
2000 - 2005
Broad application observations on 100s of patients in collaboration with complementary physicians.
2004
Foundation of the company Panaceo International GmbH at the site in Gödersdorf near Villach/Carinthia.
2006
Approval as a medical device to ensure the described efficacy and safety for the user.
2013 - 2014
Start of Austria-wide marketing and educational activities among end customers and the professional public. Research into the binding of harmful substances in the gastrointestinal tract and implementation of a non-interventional study (NIS) to support liver health.
2015
Publication of a randomized placebo-controlled double-blind (gold standard) study of effective gut-wall barrier strengthening.
2017 - 2019
Research and publish safety and efficacy-related studies related to the mode of action of PMA zeolite.
2020
Publication of a gold standard study to effectively support tolerability of drug therapies.
2021
Publication of a gold standard study for effective relief of intestinal inflammation.
2022
Publication on the improvement of bone metabolism and fracture probability in osteoporosis at the end of a long-term clinical follow-up of 5 years.
Follow-up publication to effectively support tolerability of drug therapies with a focus on relevant oncological parameters.